摘要 目的 探索老年功能性便秘患者肛门、直肠运动功能的变化。 方法 采用气囊测压管检测30例老年功能性便秘患者的肛门、直肠运动功能，并以健康人及非老年功能性便秘患者作对照观察。 结果 (1)老年健康人肛门内括约肌静息压、最大缩窄压、肛管直肠屏障压、肛管括约肌长度分别为10.1±3.0、14.7±2.3、8.0±2.8kPa和2.3±0.4cm，低于非老年健康组(P<0.05或0.01)；而直肠最低敏感量、最大顺应性(92±48、34±10ml/kPa)高于非老年健康组(P<0.05)。(2)老年便秘组肛管直肠屏障压、直肠最低敏感量、最大耐受性、最大顺应性和内括约松弛压为10.5±3.0kPa，106±42、260±50ml、37±15ml/kPa和5.9±1.0kPa高于老年健康组(P<0.05或0.01)。(3)老年便秘组直肠肛管屏障压、肛管括约肌长度和肛门内括约肌最大缩窄压小于非老年便秘组(P<0.05)。

结论 老年健康人有直肠、肛门运动功能紊乱，便秘与直肠低敏感、高耐受、高顺应性、内括约肌松弛不良有关。

Ding Yuanwei. Department of InternalMedicine, the Second Affilliated Hospital of Guangzhou Medical College, Guangzhou 510260

Abstract Objective To studythe changes of anorectal motility in the healthy elderly and elderly patients withfunctional constipation (FC). Methods Anorectal motility was investigated by multi-spot ballon probe in30 healthy elderly subjects (HE), 15 non-elderly healthy subjects (NEHS), 30 elderly and30 non-elderly patients with FC. Results 1. The static pressure and maximal squeeze pressure of internalanal sphincter (IASMSP), the anorectal barrier pressure (ABP) in HE (10.1±3.0,14.7±2.3,8.0±2.8kParespectively) were lower than those in NEHS (P<0.05or 0.01). The length of anal sphincter high zone (ASHL)in HE (2.3±0.4cm) was shorter thanthat in NEHS. The rectal lowest volume of sensory threshold (RLSTV), the maximalcompliance (MC) in HE (92±48 ......