蒋敬庭 吴昌平 陈雪勤 吴爱珍 陈国瑾 孙文辉 213003 常州市，苏州医学院附属第三医院肿瘤生物诊疗中心 中华老年医学杂志 1999 0 18 1


    关键词：胸腔积液，恶性；淋巴细胞，肿瘤浸润 期刊 zhlnyxzz 0 临床研究 fur -->


    

【摘要 】 目的 探讨肿瘤浸润淋巴细胞(TIL)治疗老年癌症患者恶性胸水的有效率。 方法 应用癌症患者自体胸水的TIL培养、扩增后产物经胸腔内输注治疗21例老年人恶性胸水，每隔日1次，至少4次。 结果 21例经治疗后，胸水中淋巴细胞增加，肿瘤细胞逐渐减少，胸腔积液逐渐吸收，1个月后19例达完全缓解和部分缓解，有效率为90.5%。 结论 自体胸水TIL可治疗恶性胸水，同时可提高老年癌症患者的免疫功能，对机体无毒副作用。

An analysis of the therapeutic effect of tumour infiltrating lymphocytes on malignant pleural effusion in aged

JIANG Jingting ,WU Changping ,CHEN Xueqin ,et al .

    The Third Affiliated Hospital of Suzhou Medical College, Changzhou 213003

【Abstract 】 Objective To study the therapeutic effect of tumour infiltrating lymphocytes (TIL) on malignant pleural effusion in aged cancer patients. Methods TIL cultured and amplified product of cancer patient's own malignant pleural effusion was used for treatment in aged cancer patients by intrapleural injection once every other day for at least four times. Results In 21 cases treated, lymphocytes in pleural effusion increased, while tumour cells gradually decreased, and pleural effusion gradually absorbed. After 1 month 19 cases were effective (90.5%). Conclusions Auto pleural effusion tumour infiltrating lymphocytes might be effective for malignant pleural effusion.

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