摘要 为了解人类巨细胞病毒(CMV)感染与糖尿病的关系，我们对845例糖尿病人和110名健康对照者CMV感染状态进行了对照研究，并根据糖尿病人的初发年龄和病程不同进行了分组研究。通过用ELISA对CMV IgM、IgA、IgG抗体检测发现：糖尿病人CMV IgM、IgA、IgG抗体阳性率明显高于对照组；发病年龄越小或/和病程越短的糖尿病人CMV IgM抗体阳性率明显升高；年龄较大或/和病程较长的病人CMV IgG抗体检出率明显升高。该结果表明：⑴CMV感染在糖尿病的发病机制中有一定的作用；⑵年龄小或/和病程短的糖尿病人以原发性CMV感染为主。

    

Epidemiologic Study of Cytomegalovirus Infection in Patients with Diabetes Mellitus Guo Teliu, Jia Heshu. Chengdu Hospital of Air Force,Chengdu 610061

    Abstract To understand the relations between human CMV infection and diabetes mellitus, 955 blood samples were tested for cytomegalovirus(CMV) antibodies from 845 diabetes mellitus and 110 healthy persons. Positive rates of CMV IgM, CMV IgA,CMV IgG antibodies were significantly higher in diabetes mellitus patients than in controls. 845 diabetes mellitus patients were devided into 4 and 5 groups according to the courses of disease and age of disease onsets respectively. Positive rates of CMV IgM antibody was significantly higher in younger patients and/or patients recently suffering from diabetes mellitus. Results showed that CMV infection was important in the pathogenesis of diabetes mellitus and primary CMV infection rates was significantly higher in younger patients and/or patients suffering from diabetes mellitus.

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