【摘要】 目的 探讨青年人胃癌的临床、病理特点。方法 1968年1月～1993年1月25年间经手术治疗、病理诊断的青年人胃癌312例,占同期收治胃癌的5.1%。将所有病例以年龄组划分为4组：≤35岁组，36～50岁组，51～65岁组，≥66岁组。对≤35岁青年人胃癌与各组进行对照观察。结果 青年人胃癌发病率女性高于男性，组织病理学类型以低分化腺癌(49.2%)、粘液细胞癌(26.6%)为多，83.3%的病例TNM分期为Ⅲ期和Ⅳ期。结论 临床晚期癌多、病理组织学分化差是青年人胃癌预后差的重要原因。提高对青年人胃癌的认识，做到早期诊断、早期治疗，是提高疗效的关键。

Gastric cancer in the young

LI Qiang, HAO Xishan, ZHANG Dekun, et al.

    Cancer Hospital, Tianjin Medical University, Tianjin 300060

【Abstract】 Objective Todetermine the clinico-pathological characteristics of young patients with gastric cnacer. Methods FromJanuary 1968 through January 1993, among 6098 gastric cancer patients admitted forsurgical treatment, 312 (5.1%) were <35 years of age. The clinico-pathological data ofthese young patients were reviewed and compared to those of patients in the other agegroups. Results In this series of young patients, female predominated. Histologically, there were more cases with poorly differentiated (49.2%) and muco-cellular(26.6%) adenocarcinoma. The most common gross morphology observed was of Borrmann type Ⅲ(38.1%)and type Ⅳ (36.9%). The mojority of patients (83.3%) were in TNM stage Ⅲ and stage Ⅳ.Conclusion The prognosis of young patients with gastric cancersurgically treated is poor. This is due to the fact that most of them are in late stageand their cancers are poor in differentiation rather than their young age. To increase theawareness of cancer in apparently healthy young persons is important for early diagnosisand treatment, and better prognosis.

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