寿建忠 马建辉 许秉责 李长岭 肖振东 田军 毕新刚 100021 北京，中国医学科学院中国协和医科大学肿瘤医院泌尿外科 中华肿瘤杂志 1999 0 21 6


    关键词：膀胱肿瘤；脐尿管肿瘤；腺癌 期刊 zhzlzz 0 临床应用 fur -->


    

【摘要】 目的 提高膀胱腺癌的诊治效果。方法 12例脐尿管腺癌中，7例行扩大性膀胱部分切除；15例原发膀胱腺癌中，11例行膀胱部分切除术。结果 膀胱腺癌总的5年生存率25.9%。脐尿管腺癌中，7例行扩大性膀胱部分切除者，无一例局部复发，12例中有4例生存5年。原发膀胱腺癌的治疗主要为膀胱部分切除术，生存5年者3例，局部复发4例，均在原肿瘤部位。1例原发膀胱腺癌皮下和腹股沟淋巴结转移患者和2例脐尿管腺癌肺转移患者经化疗+放疗后分别生存24，28和60个月。结论 脐尿管腺癌宜采用扩大性膀胱部分切除术，原发膀胱腺癌宜采用根治性膀胱全切除术。对复发转移患者应积极采取综合治疗，以提高生存率。

Adenocarcinoma ofthe urinary bladder: a report of 27 cases

SHOU Jianzhong, MA Jianhui, XU Bingze, et al. Department of Urology,Cancer Hospital, Chineses Academy of Medical Science, Peking Union Medical College,Beijing, 100021

【Abstract】 Objective To analyze thetherapeutic results of urinary bladder adenocarcinoma.Methods Twenty-sevenurinary bladder adenocarcinoma patients were treated from 1970 through 1997. There were 12cases of urachal adenocarcinoma and 15 cases of bladder adenocarcinoma. Hematuria with orwithout urinary tract irritation symptoms was the most common clinical manifestation.Results Theoverall 5-year survival rate was 25.9%. Among patients with urachal adenocarcinoma, 7received extended partial bladder resection. None of them had local recurrence. Patientswith bladder adenocarcinoma mainly received partial bladder resection, with which 4developed local recurrence at the primary site. The 5-year survival rate of urachaladenocarcinoma and bladder adenocarcinoma was 33.3% and 20.0%, respectively. One patientof bladder adenocarcinoma with skin and inguinal lymph node metastases and 2 patients ofurachal adenocarcinoma with lung metastasis treated with chemotherapy and radiotherapysurvived 24, 28 and 60 months, respectively.Conclusion Extended partialbladder resection is the treatment of choice for urachal adenocarcinoma while radicalcystectony for bladder adenocarcinoma. Comprehesive therapy should be given to patientswith metastatic or recurrent disease to improve survival.

     ......