陈书连 贺长清 吴学建 陈书连 (河南省人民医院骨科 450003)；贺长清 (吴学建河南医科大学第一附属医院骨科) 中华显微外科杂志 1998 0 21 3


    关键词：周围神经；静脉移植；雪旺细胞 期刊 zhxwwk 0 基础研究 fur -->


    

【摘 要】 目的： 探寻静脉翻转后对引导神经再生的影响，为周围神经缺损的修复提供一种新方法。方法 ：静脉段取出后，先将其内外翻转成一外膜在内，内膜在外的翻转静脉。然后再用此翻转静脉段桥接修复大鼠自体坐骨神经10mm缺损(IOVG)并与常规静脉桥接修复方法(CVG)进行对比研究。术后5个月，进行神经电生理及组织形态学检测。结果 ：与CVG相比，IOVG组再生神经纤维的数目、髓鞘厚度、纤维直径以及运动神经传导速度均有提高。结论 ：翻转静脉桥接修复周围神经缺损是一简单而有效的新方法。

AN EXPERIMENTAL STUDY OF TUBULATING A DEFECTOF PERIPHERAL NERVE WITH INSIDE-OUT VEIN GRAFT IN RAT

Chen Shulian， He Changqing, Wu Xuejian.

    Department of Orthopedics, Henan Provincial Peoples Hospital, Zhengzhou 450003

【ABSTRACT】 Objective: In order toprovide a new method to repair peripheral nerve defect, this article detects the influenceon nerve regenerating. when using inside-out vein graft to bridge the gaps in peripheralnerve. Methods : Turn the harvested vein segment to bridge 10mm defect ofsciatic nerve in rat IOVG, and compared it with convential vein grafe (CVG).By 5 monthspostoperatively, the quantitative analysis in histology and the nerve electrophysiologicaltest were performed. Results : The number, the mylin sheath thickness andthe conduction velocity of the regenerating fibers had been improved in IOVG. Conclusion： Bridging a defect in peripheral nerve with inside-out vein graft is a simple and moreeffective method.

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