关键词:肾母细胞瘤;肿瘤血管生成;免疫组织化学
摘要 目的: 探讨肿瘤内微血管计数(MVC)在肾母细胞瘤中的意义。 方法: 应用免疫组化染色对38例肾母细胞瘤进行回顾性研究。 结果: ① 预后差的间变型较预后好的各型MVC均显著增高(P?.05), 胚芽型较上皮型MVC亦显著增高(P?.05)。 ② 晚期病例较早期者MVC显著增高(P?.001)。 ③ 生存组与死亡组MVC有显著差异, 前者较低(P?.001); 高MVC组较低MVC组的生存率明显降低(P=0.0016)。 ④ 随肿瘤内炎细胞浸润程度的增加, MVC无显著变化(P>0.05)。 结论: MVC是判断肾母细胞瘤预后一较理想的指标。
The Significance of Microvessel Count in Nephroblastoma Yuan Feng , Chen Yuli, Liu Hongqi, et al. Dept. of Pediat. Surgery, The Affiliated Hospital of Shandong Medical University, Jinan 250012
Abstract Objective: To study the significance of microvessel count (MVC) in nephroblastoma. Methods: MVC was retrospectively measuredin 38 cases of nephroblastoma by SP procedure. Results: 1. MVC of nephroblastoma with unfavourable histology was significantly higher than that with favourable histology (P?.05) and MVC of blastemal type was significantly higher than that of epithelial type (P?.05). 2. MVC of nephr
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