鲍南 施诚仁 金惠明 宋家其 上海第二医科大学附属新华医院小儿外科 200092 中华小儿外科杂志 1999 0 20 6


    关键词：神经管缺陷；生活质量；儿童 期刊 zhxrwkzz 0 临床研究 fur -->


    

【摘要 】 目的 对神经管缺陷患儿生活质量作一评价。方法 1983年1月至1997年12月随访105例神经管缺陷患儿,年龄1天～11岁，采取门诊随访及信访方式, 时间3个月～14年，平均(3.89±3.53)年。结果 77.22%的患儿生活质量下降, 主要表现在运动功能、括约肌功能、性功能及智力方面。病变部位越高, 生活质量越低下; 伴有脑积水的患儿智商较易受影响。结论 神经管缺陷患儿多数留有后遗症,其严重程度主要与病变部位、病变类型及脑积水有关。

    Neural Tube Defects:Quality of Life Assessment

BAO Nan, SHI Chengren, JIN Huiming, et al.

    Department of Pediatric Surgery, Xinhua Hospital, Shanghai Second Medical University,Shanghai 200092

【 Abstract 】 Objective To assess the quality of life andthe efficacy of treatment for children suffering from neural tube defect. Methods One hundred and five childrenwith neural tube defect who were managed in our hospital from Jan. 1983 to Dec. 1997. Themean age (± standard deviation) at presentation was (2.13±2.64)years, ranging from 1 dayto 11 years. They were followed-up for a mean (±standard deviation) of (3.89±3.53)years,ranging from 3 months to 14 years. Results 77.22% of the children have compromised quality of life,exemplified by limited ambulance, incontinence of urine and feces, sexual dysfunction andmental retardation. The higher the level of neural tube defect, the worse the quality oflife. Those with hydrocephalus are more likely to develop mental retardation. Theneurological deficits were evident at birth in 49.18% of children whereas the remainingdeveloped the symptoms in the following 5 months. Conclusions Most children with neural tube defect have residualneurological deficit. The degree of neurological disability is related to the level of thepathology and hydrocephalus. Early operative intervention may minimize the residualneurological deficits.

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