关键词：重症肌无力；认知障碍；神经心理学测验
【摘要 】 目的 研究重症肌无力(MG)病人智力、记忆力等认知功能及情感。方法 采用龚氏修订的韦氏成人智力量表中国版、记忆量表中国版及抑郁自评量表，对31例MG病人及相匹配的22名正常对照以及25例其他疾病组进行检查研究。结果 MG组大部分分测验值明显低于正常对照组及其他组，存在智力下降14例，其中智力缺陷6例；记忆力下降24例，其中记忆力明显损害19例，尤以短时记忆及瞬时记忆下降明显，全身型记忆力损害较眼肌型多。有主观抑郁症状者13例。结论 MG病人中枢神经胆碱能系统可能受到损害，进而导致认知功能障碍
Intelligence，memory and emotiondysfunction in patients with myasthenia gravis
ZHENG Jinou, MO Xuean, MA Chaogui,et al.
Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530027
【Abstract 】 Objective Tostudy the intelligence, memory and emotion in patients with myasthenia gravis(MG). Methods Wechsleradult intelligence scale RC, Wechsler memory scale RC and self depression scale were usedto detect 31patients with MG and 22 healthy control subjects and 25 medical controlsubjects. Results In the majority of the test data, in the MG patientgroup were significantly lower than those in healthy control group and the medical controlgroup respectively. 14 MG cases had intelligence impairment and among them 6 MG cases hadintelligence deficit, whereas 24 MG cases had memory impairment and among them 19 MG caseshad significantly memory impairment, with recent memory more significantly impaired thanlong memory, and with memory damage more in the general body type than in the eye muscletype. 13 MG cases had subjective depression symptoms. Conclusion Theresults support the idea that MG had central cholinergic impairment that might result incognitive dysfunction.
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