徐东 吴志兴 冷珍璞 李绍芝 张秀敏 徐东 冷珍璞 张秀敏 250021 济南，山东省立医院神经内科；吴志兴 李绍芝 核医学科 中华神经科杂志 1999 0 32 5


    关键词：脑出血；脑梗死；肾循环；肾小球滤过率 期刊 zhsjkzz 0 论著摘要 fur -->


    

【摘要 】 目的 探讨急性脑血管病患者伴肾功能异常的机制及早期监测指标。方法 应用^99m Tc-DTPA肾动态显像观察148例急性脑血管病(脑梗死80例、脑出血68例)及64名健康人的肾小球滤过率(GFR)及综合清除曲线等指标。结果 急性脑血管病患者存在不同程度的肾血流灌注障碍，43.7%(35/80)的脑梗死和38.2%(26/68)的脑出血患者GFR异常，脑梗死组病灶对侧GFR降低，急性脑血管病的肾综合清除曲线异常，以抛物线型和排泄延迟居多。结论 肾功能显像有助于早期发现肾功能损害；治疗脑血管病的同时应注意保护肾功能。

The renal perfusion in patientswith acute cerebrovascular diseases

XU Dong, WU Zhixing, LENG Zhenpu,et al.

    Department of Neurology, Shandong Provincial Hospital, Jinan 250021

【Abstract 】 Objective Toexplore the mechanism and the early indicator of the renal impairment associated withacute cerebrovascular disease (ACVD). Methods With ^99m Tc-DTPAdynamic renal imaging,we evaluated the renal function of the ACVD (148 cases) and thecontrol group (64 cases). Result The renal perfusions of ACVD showedsome disturbances.The glomerular filtration rate (GFR) of cerebral infarction (43.7%) andcerebral hemorrhage (38.2%) were abnormal.Particularly in the infarction group,thecontralateral GFR of the brain lesion decreased. The abnormalities of the renal clearancecurve were mainly in the shape of a parabola with the delay of elimination. Conclusion Thesesuggested that radionuclide renal imaging would facilitate the early diagnosis of therenal impairment,and in the therapy of the ACVD the renal function should be protected.

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