杨光成 司徒朴 陈兵 张余光 杨光成 广州军区总医院整形外科(广州，510010)；司徒朴 陈兵 张余光 第一军医大学珠江医院整形外科 中国修复重建外科杂志 1999 0 13 3


    关键词：引导性骨组织再生；膜技术；聚乳酸；羟基磷灰石 期刊 zgxfcjwkzz 0 骨组织缺损的修复 fur -->/info/meeting/meeting02.asp?keyword=整形外科学


    

【摘 要】 目的 证实膜引导性组织再生现象存在于骨缺损的愈合过程中，并探讨其机理。方法 采用新西兰大白兔为实验对象，将兔桡骨制成1 cm缺损，一侧用羟基磷灰石/聚乳酸膜(HA/PLA)包绕缺损，另一侧作为对照，通过X线片、大体观察及病理检查等观察两侧桡骨愈合情况。结果 对照侧均呈现骨不愈合现象，实验侧有不同程度的骨愈合现象。结论 膜技术的应用有利于骨缺损的愈合。

THE EXPERIMENTAL STUDY OFMEMBRANE-GUIDED

    TISSUE REGENERATION O F BONE

YANG Guang-cheng,SITU Pu,CHENBing,et al.

    Depar tment of Plastic Surgery,General Hospital of Guang zhou Military Region.Gu angzhouGuangdong,P.R.China 510010

【 Abstract】 Objective To confirm membrane-guided tissue regeneration in the healingcourse of segme nt al bone defects and study the mechanism.Methods Segm enta l,1 cmosteoperiosteal defects were produced in both radii of 12 rabbits.One sid e was coveredwith hydroxyapatite/polylactic acid(HA/PLA) membrane encapsulated as a tube.Thecontralateral side served as an untreated control.Healing courses were detected byradiographic and histologic examinations.Results All control sides showed nonunion,whereas there wereconsistent heali ng pattern in test sides.Conclusion Membrane technique can promote bone regeneration.

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