抑郁症的强迫症状及强迫与抑郁关系的研究
抑郁症|强迫|病例对照研究|症状分析|精神病理学,关键词：
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关键词：抑郁症；强迫；病例对照研究；症状分析；精神病理学
【摘要】 目的 探讨伴强迫症状抑郁症的症状学特征及其精神病理关系。方法 对43例伴强迫症状抑郁症患者(抑郁伴强迫组)的强迫与抑郁症状进行相关分析，并与50例不伴强迫症状抑郁症(抑郁无强迫组)及30例强迫症患者(强迫症组)作病例对照研究。结果 抑郁伴强迫组的强迫症状与HAMD总分及焦虑/躯体化、认识障碍因子显著相关，在抑郁状态中的再现率为86%。临床表现以焦虑、疑病、偏执症状、自杀明显，强迫症状以纯强迫观念多见，且具有症状持续时间长，治疗后显效慢的特点。强迫症组的强迫和焦虑评分较高，表现为相对的连续性病程。结论 抑郁伴强迫组的强迫症状是抑郁症状的一部分，对抑郁特征有一定影响，与强迫症组的强迫症状比较有质的差异。症状学研究对临床分型诊断和治疗有重要意义。
A studyof the obsessive symptoms and their relationship with depressive symptoms in depressiondisorder
Chen Zhien Lu Zilu Mei Yintai Zhang Jin
( The Second People s Hospital of Lishui District Zhejiang. 115 Dayang Road, Lishui. 323000. Tel:0578-2128415 )
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Abstract 】 Objective To explore the relationshipbetween symptoms and psychopathology of depression with obsessive symptoms. Methods The obsessive anddepressive symptoms in 43 cases of depression with obsessive compulsive symptoms wereanalyzsed and compared with 50 cases of depression without obsessive symptoms and 30 casesof pure obsessive compulsive disorders (OCD). Results The Y-BOCS score of depressivepatients with obsessive features was noticeable and was correlated with the score of HAMD, anxity/somatization and cognitive disorder. The rate of obsessive symptoms in depressivestate was 86%. Depressive with obsessive symptoms had simpler obsession than OCD, and hadmore marked manifestations of anxity, hypochondriasis, paranoid symptoms, suicide, andlonger duration of symptoms. The effect of treatment also appeared slower than depressionwithout obsession. The score of obsession and anxiety was the highest and the course ofillness was the longest of the three groups. Conclusions The obsessive symptoms indepression with obsession was a part of depressive symptoms and certainly affected thedpressive featurese. They differed from the obsessive symptoms of pure OCD in nature. Thestudy of symptomatology of these overlapping disorders may help refine clinicalclassification, diagnosis and treatment.【 Key words 】 DepressionObsessive Case-control study Symptomatic analysis Psychopathology ▲
自从Neiman(1980)提出强迫与抑郁为常见的共存症状以来 ......
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