王群 刘继元 兰海梅 王群 刘继元(510515 广州市,第一军医大学附属南方医院神经内科)；兰海梅(皮肤科) 中国超声医学杂志 2000 0 16 6


    关键词：经颅多普勒；红斑狼疮 期刊 zgcsyxzz 0 451-452 临床研究 fur -->


    

摘 要 目的：了解系统性红斑狼疮患者脑血流动力学状况。方法：利用经颅多普勒(TCD)测定红斑狼疮患者和健康对照组脑血管收缩峰速度(Vs)、舒张期血流速度(Vd)、平均血流速度(Vm)、收缩/舒张比值(S/D)、血管搏动指数(PI)、阻力指数(RI)。结果：红斑狼疮患者无论Vs、Vm是否升高,各脑血管Vd均较对照组显著增快(P<0.01);PI、RI显著降低(P<0.01),突出表现为低阻力的TCD频谱改变。结论：红斑狼疮患者脑血流动力学发生明显变化。

Examination of CerebralHemodynamics in Patients with

    Systemic Lupus Erythematosus by Transcranial

    Doppler Ultrasonography

Wang Qun,Liu Jiyuan,Lan Haimei

    Department of Neurology,Nanfang Hospital,Guangzou 510515 China

ABSTRACT Objective:To investigate thecerebral hemodynamic changes in 19 patients with systemic lupus erythematosus(SLE).Methods：Thesystolic peak velocity(Vs),end-diastolic flow velocity(Vd),mean flow velocity(Vm),systolic/diastolic ratio(S/D),pulsatility index(PI)and resistance index(RI)of intracranial arteries in the patients with SLE and healthy control were examinated bytranscranial Doppler ultrasonography(TCD).Results:Vd in the patients was increased markedly,S/D,PI and RI were reduced obviously.Conclusion:The data showed cerebralhemodynamic TCD changes are characteristic in SLE.

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