【摘要】

    目的 探讨重症急性胰腺炎(SAP)合并深部真菌感染的危险因素、诊断、治疗及预防措施。

    方法 回顾性分析我院1998年8月～2005年4月收治的102例SAP病例。

    结果 合并深部真菌感染的40例患者中，死亡15例(37.5%)。共培养出55株真菌菌株，均为念珠菌，真菌检出时间平均为(12.5±5.6)天。

    结论 SAP合并深部真菌感染应引起足够重视，提倡早期预防、早期诊断及早期应用抗真菌药物，同时结合必要的病灶清除和早期肠内营养支持，可减少SAP合并深部真菌感染的发生及其导致的严重后果。

    【关键词】 重症急性胰腺炎；真菌感染；诊断；治疗

    The diagnosis and treatment of fungal infection in severe acute pancreaTitis

    WU Yang.

    Department of General Surgery,The First Affiliated Hospital of Zhengzhou University,Henan 450052,China

    【Abstract】

    Objective To investigate the risk factors,diagnosis,treatment of fungal infection in severe acute pancreatitis(SAP),and its preventive strategy.

    Methods Retrospective analysis of 98 cases of SAP admitted from Aug 1998 to Apr 2005 in the first affiliated hospital of Zhengzhou University.

    Results Fifteen cases (37.5%) died in the group which was forty patients of fungal infection in SAP.Fifty-five fungus were cultured and all of them were candida.The average time that fungus were cultured was 12.5±5.6 days.

    Conclusion We should pay more attention to fungal infection in SAP.The treatment of SAP should be include diagnosis,prophylactic treatment of fungal infection in early,combine with eliminating focus and enteral nutrition in early.It can decrease the incidence and serious complications of fungal infection. ......