【摘要】目的观察红霉素、顺铂和高渗葡萄糖三联行胸膜粘连术治疗大量恶性胸腔积液的疗效。方法48例患者均采用胸腔闭式引流术，注入红霉素、顺铂、50%葡萄糖液、利多卡因，每周1次。结果红霉素、顺铂和50%葡萄糖液三联行胸膜粘连术治疗恶性胸腔积液总有效率为91.7%，其中完全缓解29例(60.4%)，部分缓解15例(31.3%)。结论红霉素、顺铂和高渗葡萄糖三联行胸膜粘连术治疗恶性胸腔积液，疗效满意，安全。

    关键词:红霉素;顺铂高渗葡萄糖;胸膜粘连术;恶性胸腔积液

    Pleurodesis in treatment of malignant pleural effusion

    Ou Xianglin，Zeng Xiangyi，Li Yuandong

    The First People’s Hospital of Shaoguan,Gangdong 512000.

    【Abstract】ObjectiveTo investigate the clinical effects of pleurodesis with erythromycin,cisplatin and 50% glucose on malignant pleural effusion.MethodsClosed thoracic drainage was used on 48 cases with malignant pleural effusion.The drugs of erythromycin,cisplatin,50% glucose and lidocaine were infused into the thoracic cavity once a week.ResultsThe total effective rate was 91.7% among which 29 cases(60.4%)total remittent,15 cases(31.3%)partial remittent.ConclusionThe clinical effects of pleurodesis with erythromycin,cisplatin and 50% glucose on malignant pleural effusion is efficient and safe. ......