【摘要】 目的 为研究山楂和山楂叶的抗氧化作用。 方法 本实验选用Wistar雄性大鼠作为研究对象。使用高脂饲料喂养的同时，用不同剂量的山楂和山楂叶提取物灌胃。5周后测定大鼠血清中的超氧化物歧化酶(SOD)以及血清中谷胱甘肽过氧化物酶(GSH-Px)活性;同时对山楂和山楂叶的抗氧化指标进行比较。 结果 山楂和山楂叶提取物能增强GSH-Px的活性，提高SOD的活力;山楂叶GSH-Px的活力高于山楂。 结论 本文提示山楂和山楂叶具有抗氧化的作用。

    【关键词】 山楂和山楂叶;SOD;GSH-Px

    Effects of haw and hawthorn leaf extracts on serum SOD and GSH-Px in rats

    ZHANG Shu-hua，CHU Jin-hua，WANG Hui，et al.

    College of Public Health and Family Medicine，Capital Uni-versity of Medical Sciences，Beijing100054，China

    【Abstract】 Objective Male Wistar rats were used as experimental subject to investigate the antioxidation effect of haw and hawthorn leaf extracts.Methods The rats were feeding on a high-fat diet for5weeks，while different dos-es of the two kinds of extracts were administered respectively by gavage once a day.Then serum SOD and GSH-Px activity were determined.Results It showed that both haw and hawthorn leaf extracts can increase the activity of SOD and GSH-Px ......