摘要:目的 探讨重组人白细胞介素-2(IL-2)在干酪性肺炎治疗中的作用。 方法 采用随机配对方法将45例干酪性肺炎患者分为治疗组(A)、间歇治疗组(B)、对照组(C)三组。 结果 A、B组痰菌涂片和培养转阴率分别为100.0%、100.0%和79.0%、66.6%;C组则分别为26.7%、33.4%，A、B组与C组存在显著性差异(P<0.05);肝功能损害率和停药率三组分别为0、6.7%、26.7%;治疗组(A+B)总有效率90.0%，C组则为66.7%。 结论 IL-2提高了干酪性肺炎的治愈率和痰菌阴转率，降低了肝功能的损害率，对临床有重要的意义。

    关键词:干酪性肺炎;重组人白细胞介素-2;疗效

    The effect of recombinant human interleukin-2in treatment of caseous pneumonia.

    ZHENG Jun，HUANG Wen-yan.(Zhaoqing Municipal Institute for Control of Tuberculosis，Zhaoqing526020，Guangdong，P.R.China)

    Abstract:Objective To investigate the effect of interleukin-2(IL-2)in the treatment of caseous pneumonia. Methods Forty-five caseous pneumonia patients were divided randomly into treatment group(A)、intermittent treatment group(B)、control group(C). Results The negative rate of sputum smear and culture of group A、B were100%、100%and79.9%、66.6%.But the group C were26.7%and33.4%.There are remarkable difference between group A、B and group C(P<0.05).The rate of liv-er function lesions and quit in the3groups were0、6.7%、26.7% ......