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老年急性白血病62例临床分析
http://www.100md.com 《中华实用医药杂志》 2005年第15期
临床分析,,老年;急性白血病;临床分析,1临床资料,2讨论,【参考文献】
     【摘要】 目的 分析老年急性白血病的临床特点、评价疗效。 方法 对初治的老年急性白血病62例进行临床分析,其中男43例,女19例,急性髓细胞性白血病(AML)58例,急性淋巴细胞白血病(ALL)4例,治疗以支持治疗,小剂量三尖杉、Ara-C单药化疗、DA,HA联合化疗。M3以维甲酸诱导缓解。 结果 AML组缓解率46.2%,ALL组缓解率75%,发生感染者42例,占67.7%。 结论 老年急性白血病对化疗反应差,缓解率低,生存期短,治疗应具个体化。

    【关键词】 老年;急性白血病;临床分析

    SHEN Qi,CHEN Mei,YU Gen-ying,et al.

    Department of Hematology,Central Hospital of Yangpu District,Shanghai200090,China

    【Abstract】 Objective To analyze the clinical characteristics of acute leukemia in elderly patients and observe their treatment effects.Methods 62cases(male43,female19)of newly diagnosed acute leukemia were evaluated,acute myelocytic leukemia(AML)werediagnosed in58patients and acute lymphocytic leukemia(ALL)in the other4patients.Supportive therapy,chemotherapy with HA,DA regimens and small dose harringtonine or small dose Ara-C were given to the patients according to their disease types and their relevant hysical conditions.All-trans retinoic acid were given to patients with acute promyelocytic leukemia(APL).Results CR rate was46.2%in AML group and75%in ALL group.Infections presented in42patients(67.7%).Conclusion Acute leukemia of the elderly pa-tients had a poor response to chemotherapy ......

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