善宁对急性胰腺炎患者血小板参数变化的影响
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黄 坚， 陆士奇， 陈建荣
急性胰腺炎;善宁;血小板计数;平均血小板体积;血小板分布宽度,黄坚，陆士奇，陈建荣，,通讯作者：,电话：,传真：,收稿日期：,接受日期：,Effectsofo
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黄坚， 陆士奇， 陈建荣，苏州大学附属第一医院急诊内科 江苏省苏州市 215006
通讯作者：黄坚，215006，江苏省苏州市，苏州大学附属第一医院急诊内科. huanganran2004@yahoo.com.cn
电话：0512-67790752 传真：0512-65292927
收稿日期：2005-08-03 接受日期：2005-08-26
Effects of octreotide on platelet parameters in patients with acute pancreatitis
Jian Huang, Shi-Qi Lu, Jian-Rong Chen
Jian Huang, Shi-Qi Lu, Jian-Rong Chen, Department of Emergency and Internal Medicine, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
Correspondence to: Jian Huang, Department of Emergency, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China. huanganran2004@yahoo.com.cn
Received: 2005-08-03 Accepted: 2005-08-26
Abstract
AIM: To investigate the changes of platelet parameters in patients with mild and severe acute pancreatitis (MAP and SAP) after treated with octreotide.
METHODS: The full-automatic blood cell counter was used to obtain the platelet count (PLT), mean platelet volume (MPV), and platelet distribution width (PDW) in the patients with MAP and SAP before and 1 wk after treatment with octreotide.
RESULTS: The platelet parameters of the patients with MAP were not significantly different from that of the normal controls. One week after treatment, there was still no significant change in the PLT. However, the MPV and PDW were increased markedly (10.88±2.40 vs 10.11±1.66, P <0.05; 17.98±4.41 vs 16.62±1.38,P <0.05). In patients with SAP, the PLT was decreased markedly (161.61±68.30 vs 191.60±31.98, P <0.05), and the MPV and PDW were increased markedly (11.82±2.33 vs 9.81±0.79, P <0.01; 19.33±7.07 vs 16.36±0.51,P <0.05) as compared with those in the normal controls. One week after treatment, the PLT was notably elevated (251.61±84.07 vs 161.61±68.30, P <0.01), while the MPV and PDW were not changed (P >0.05) as compared with those before treatment ......
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