摘 要：目的：研究神经妥乐平治疗急性缺血性脑卒中的可行性和有效性。方法：对50例发病48h内，神经功能评分<80分，病灶面积>2.25cm2的急性颈内动脉梗塞的患者进行随机分组试验(神经妥乐平治疗组31例，对照组19例)。测定治疗前后不同阶段神经功能缺损评分、日常生活能力、CT病灶面积和平均CT值，并进行统计学分板。结果：治疗组神经功能改善率为64.5%，对照组为31.6%；11d时梗塞水肿面积治疗组已缩小28.8%，且平均CT值明显提高，改善程度明显优于对照组。结论：neurotropin可作为治疗急性缺血性脑卒中和缺血性脑水肿的有效方法。

    关键词： 缺血性脑卒中； 脑水肿； 神经妥乐平

    Observation on Treatment of Neurotropin to Ischemic Stroke

    MAO Jian- hua

    (Chang'an Hospital of Dongguan,Guangdong Dongguan 523843, China)

    Abstract：Objective： To study the feasibility and efficiency of neurotropin in treatment to patients with acute moderate and severe ischemic stroke.Method： Randome control trial of Neurotropin was performed in 50 patients admitted within 48h after acute internal carotid artery infarction.As neurological deficits score(Europe Stroke Scale,ESS) <80 and the area of infarct and edema area>2.25cm2 all patients were divided in neurotropin group(31)and control group(19).we evaluated,ability of daily living(ADL)-Bar-thel index,and the size and average CT density of infarct and edema area. Result： The percentage of improved patients(complete and partial recovery)reaches 64.5% in the neurotropin group and 31.6% in the control group.The size of the infarct and edema area on CT scan significantly reduced only in the neurotropin group after treatment,which reduced to 28.8%on dll.the average CT density in the neurotropin group improved much more than in the control group.Conclusion： Neurtropin can be used as an effective therapy in acute ischmic stroke and ischemic cerebral edema. ......