摘要：目的：探讨热性惊厥时异常脑电图(EEG)与以后癫痫的发作，与热性惊厥的再发及预防性治疗的关系。方法：对250例6个月至6岁患儿的热性惊厥后的脑电图。结果：首次EEG异常率为45%，EEG异常率与I级亲属的热性惊厥史关系，EEG异常与热性惊厥的临床特征(局限性发作和热性惊厥持续时间>15min)的关系，随着发热再发次数的增多逐渐增高，再发3次以上的患儿中，其EEG异常率高达40%～60%，3岁以上热性惊厥儿童其EEG异常率明显增多，部分患儿多次EEG检查出现发作性棘尖波、棘(尖)慢综合波，其中10例随访3～5年，最后诊断为癫痫。结论：EEG异常率与I级亲属是否有热性惊厥史有关，与高热临床特征有关，热性惊厥再发与EEG异常，年龄有明显关系，EEG多次异常，发热可发展为癫痫，建议预防性治疗。

    关键词：高热惊厥；脑电图；再发；癫痫

    Analysis of Electroencephalogram in 250 Children with Febrile Convulsion

    ZHANG Yue

    (Maoming People's Hospital, Guangdong Maoming 525000, China)

    Abstract： Objective: To study the relationship between abnormal electroencephalogram(EEG) of febrile convulsion (FC) children and their further seizures , relapse as well as preventive treatment. Method:The EEG in 250 FC children at the age of 4 month to 6 years was recorded.Rseult: In first time of FC children , abnormality rate of EEG was 45%; There was relationship between abnormality rate of EEG and the FC history of their I grade relatives ,but it was related to clinical feature of FC (local seizures and FC lasting >15min);The first time abnormality rate of EEG was 22%,and it increased with FC repeat times increasing , in >3 times FC, the abnormality rate of EEG ould be 40%～60%; The abnormal EEG was not significant negative in FC children less than 3 years but become significant after 3 years old , some children 10 of them become to be epileptic patients 3～5years later . Conclusion: There might be relationship between abnormality rate of EEG and FC history of their I grade relatives , abnormality rate of EEG might be related to clinical feature of FC; further seizures might be related to abnormal EEG and ages;several times of abnormal EEG can lead to epilepsy. ......