8种中药水煎剂与免煎颗粒剂对临床菌株的体外抑菌作用研究
中药水,,中药水煎剂；免煎颗粒剂；抑菌作用；最低抑菌浓度,1实验材料,2实验方法,3结果,4讨论,参考文献：
摘要：目的：比较8种中药的水煎剂与免煎颗粒剂对56株临床分离金黄色葡萄球菌的体外抑菌效果。方法：采用M-H琼脂稀释法检测8种中药水煎剂与免煎剂对MSSA，MRSA的抑菌作用，测定最低抑菌浓度MIC50和MIC90，并加以比较。结果：8种中药抑菌强度不同，五倍子抑菌效果最好；除五倍子、连翘外，其余中药水煎剂抑菌效果比相应的免煎颗粒剂好。结论：中药水煎剂与免煎颗粒剂抑菌效果的差异，可能与制备工艺及原药材品质有关。关键词：中药水煎剂；免煎颗粒剂；抑菌作用；最低抑菌浓度
The in Vitro Antibiotical Effect of the Single Chinese Herbal Decoction and the Single Herbal Concentrate-granules against Clinical Bacterial Strains
WANG Yuhong, ZHANG Zhiqing, LI Zhongxing, WANG Xiuhua
(The Second Hospital of Hebei Medical University,Shijiazhuang 050000, China)
Abstract:Objective:To compare the in vitro antibiotical effect of Chinese herbal decoction and single herbal concentrate-granules for 8 traditional Chinese medicines against clinical Staphylococcus aureus Rosenbach.Methods:The antibiotical effect of single herbal decoction and single herbal concentrate-granules for 8 traditional Chinese medicines against MSSA and MRSA was detected and compared by M-H agar dilution method,with MIC50 and MIC90 determined.Results:Eight traditional Chinese medicines showed different antibacterial activities ,with Galla Chinensis being the most potent.The antibiotical effect of single herbal decoction was better than that of single herbal concentrate-granules for Chinese traditional medicines except Galla Chinensis and Fructus Forsythiae.Conclusion:Difference of antibiotical effect between single herbal decoction and single herbal concentrate-granules maybe related to preparation technologies and qualities of raw medicinal materias. ......
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