【摘要】 目的 评价侧开胸手术后肋间神经冷冻镇痛效果及其安全性。方法 对138例开胸患者进行随机前瞻性研究。术前将患者随机平均分为3组：组1(46例)为肋间神经冷冻组；组2(46例)为硬膜外置管给药组；组3(46例)为肌注给药组。比较3组镇痛的效果、镇痛相关并发症及对呼吸系统并发症的影响。结果 组1的镇痛效果明显优于组2和组3(P<0.05)；组1的镇痛相关并发症及呼吸系统并发症的发生也少于另两组(P<0.05)。结论 肋间神经冷冻是一种安全有效的防治侧开胸手术后切口疼痛的方法。

    【关键词】 侧开胸手术后；肋间神经冷冻；硬膜外镇痛

    Prevention of incision pain after thoracic surgery by using of cryoanalgesia to intercostals nerve

    PAN Tie-cheng,CHEN Tao，XU Qin-zi,et al.

    Cardiothoracic Department of Tongji Hospital，Tongji Medical College，HUST,Wuhan 430030,China

    【Abstract】 Objective To evaluate the result and the safety of cryoanalgesia in thoracic surgery.Methods A random prospective study was performed on 132 patients after thoractomy. Patients were divided into 3 groups(each group was 46 patients): group 1 received intercostals nerve freezing; group 2 used patient controlled epidural analgesia; while patients in group 3 received analgesic intramuscularly when needed. Effectiveness of different analgesia methods and their influence on postoperative complications were compared.Results Analgesia effects in group 1 were much better in than group 2 and group 3; at the same time, postoperative complications were much less in group 1 than in the other two groups.Conclusion Cryoanalgesia to intercostals nerve is safe and effective on prevention of incision pain after thoracic surgery. ......