摘要：目的：分析COPD患者抗生素相关性腹泻的发病率、发病因素，进一步探讨抗生素应用对腹泻严重程度的影响。方法：对我院呼吸内科病房5年内123例COPD患者合并抗生素相关性腹泻的临床资料进行回顾性分析。结果：抗生素使用时间≥7d,腹泻发生率明显升高,联合使用抗生素种类越多,腹泻发生率越高。结论：合理使用抗生素,严格控制广谱抗生素的使用,是预防控制医院感染抗生素相关性腹泻的关键措施。

    关键词：COPD；腹泻；抗生素

    The Investigation of Antibiotic-Associated Diarrhea in 123 COPD Patients

    ZHANG Ying, TAN Jin-wen, ZHAO Zi-wen, et al

    (The First Municiple People’s Hospital of Guangzhou City,Guangdong Guangzhou 510180,China)

    Abstract: Objective: To analyze the incidence and factors of antibiotic associated diarrhea (AAD), In addition, to investigate the effect of antibiotics on the degree of diarrhea. Method: To measure retrospectively the clinic findings of COPD patients complicated with AAD in respiratory department wards within 5 years.Result: The incidence of AAD was markedly high when the length of the antibiotic treatment was ≥7 days, the more kinds of the combined antibiotics the more incidence of the AAD. Conclusion: It was the key management of preventing and controlling AAD that appropriate antibiotic practice was aware and the broad-spectrum antibiotic was strictly controlled. ......