食管_____食管肿瘤;_外科治疗;

原发性食管腺癌的外科治疗(附25例报告)

http://www.100md.com 《新疆医科大学学报》 2005年第7期

食管,,食管肿瘤;,外科治疗;,预后,1资料与方法,2结果,3讨论,参考文献:

     摘要: 目的：探讨原发性食管腺癌的外科治疗经验及其临床生物学特征和影响患者生存期的相关因素。方法：对外科治疗的25例原发性食管腺癌的发病情况、组织来源及治疗方法进行回顾性分析，病理分期：Ⅰ期2例，Ⅱa期2例，Ⅱb期5例，Ⅲ期14例，Ⅳ期2例。根治性手术19例，姑息性手术6例。结果：经手术病理证实的25例腺癌，占同期手术1 350例食管癌的1.85%。术后1、3、5年生存率分别为80.4%、36.0%、20.0%，术后并发症发生率为8.0%。结论：食管腺癌和食管鳞癌相比恶性程度高,病变进展快,预后差。影响手术后长期生存的重要因素为TNM分期、有无淋巴结转移、肿瘤外侵程度和手术方式。提高食管腺癌的早期发现率和以外科手术为主的综合治疗是改善术后远期疗效的关键。

    关键词：食管肿瘤; 外科治疗; 预后

    Surgical treatment of primary esophageal adenocarcinomaanalysis of 25 casesZHANG Zhu, WU Mingbai, ZHANG Changming, et al

    (Department of Thoracic Surgery, First Affiliated Hospital, Xinjiang Medical University,

    Urumqi 830054, China)Abstract: Objective: To explore surgical treatment of primary esophageal adenocarcinoma (PEAC) and to investigate the clinical biocharacteristics and factors influencing patients’ survival. Methods: Twentyfive cases of PEAC undergone surgical treatment were analysed retrospectively. Result: Twentyfive cases of PEAC consisted of 1.85% of 1350 cases of pathologically confirmed esophageal carcinoma. The TNM staging (UICC 1977): 2 cases were in stage 1, 2 in stage Ⅱa, 5 cases in stage Ⅱb and 16 cases in stage Ⅲ. The 5year survival rates of them were 20.0%. Conclusion: Compared with esophageal squamouscell carcinoma, PEAC is a malignant disease with esophageal squamouscell carcinoma, PEAC is a malignant disease with poor prognosis. The TNM staging, lymph node metastasis, extraesophageal extension of the primary tumor and mode of operation are the important influencing factors in the longterm survivals. The longterm survivals may be increased by early detection of PEAC, early surgical intervention and adjunct multimodality treatment. ......

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