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左卡尼汀对血液透析患者心功能的作用
http://www.100md.com 《滨州医学院学报》 2005年第5期
尿毒症,,心功能;尿毒症;血液透析;左卡尼汀,1临床资料,2结果,3讨论,参考文献
     【摘要】 目的 探讨左卡尼汀对慢性肾衰竭透析患者心功能的作用。方法 维持性血液透析患者58例,分为治疗组30例,对照组28例。治疗组于透析结束前静脉注射左卡尼汀10 g,每周3次,疗程3个月;对照组注射等量的生理盐水。用心功能检测仪测定患者每搏心输量(SV)、每分钟心搏量(CO)、心脏指数(CI)、左心功能指数(QZ)、心肌收缩力(DZ/DT)、心缩力指数(HI)。结果 治疗组精神状态、体力明显改善,心肌收缩力增强,心功能指数较治疗前及对照组明显改善(P<001)。结论 左卡尼汀可改善透析患者的心功能。

    【关键词】 心功能;尿毒症;血液透析;左卡尼汀

    Effect of Lcarnitine on cardic function in patients with hemodialysis

    LIU Yuxia1 ZHU Liqin2 LIU Yunqi1 et al

    1 Department of Nephrology,Affiliated Hospital of Binzhou Medical College,Binzhou 256603;2 People's Hospital of Binzhou City

    【Abstract】 Objective To investigate the cardiac function improving effect of Lcarnitine in hemodialysis patients.Methods fiftyeight patients on maintaining hemodialysis were divided into twogroups,treatment group (n=30) and controk group (n=28).10 g of Lcarnitine was infused to the patients in treatment group at the end of dialysis three times a week for 3 months.While normal saline was given to the control group.Cardiac function indexes SV,CO,CI,QZ ......

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