重叠综合征20例临床分析
重叠综,,阻塞性睡眠呼吸暂停综合征；重叠综合征；持续正压通气,1资料和方法,2结果,3讨论,参考文献：
摘要： 目的： 讨论重叠综合征患者的临床特点及经鼻持续正压通气(continue positive airway pressure, CPAP)对重叠综合征的治疗效果。方法： 对80例单纯阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome, OSAS)与20例重叠综合征(Overlap Syndrome, OS)患者的并发症、体重指数、病史年限、呼吸紊乱指数、睡眠期最低血氧饱和度等行分析对比，并应用CPAP对20例重叠综合征患者进行治疗。结果： 重叠综合征患者冠心病、高脂血症、红细胞增多症、蛋白尿的发生率较单纯阻塞性睡眠呼吸暂停综合征者更高，体重指数、病史年限、睡眠期最低血氧饱和度等指标，两组比较差异有统计学意义(P<0.05)，应用CPAP治疗20例重叠综合征患者疗效明显，睡眠期最低血氧饱和度、呼吸紊乱指数、低通气指数均下降。结论： 重叠综合征患者有显著的临床特点，并发症多且严重， CPAP是治疗重叠综合征的有效方法。关键词： 阻塞性睡眠呼吸暂停综合征；重叠综合征；持续正压通气
Study on clinical characteristics and curative effect of overlap syndrome patients with continue positive airway pressureWU Li, HUANG Xiangzen
(Department of Pulmonology, Second Affiliatal Hospital, Xinjiang Medical University, Urumqi 830028, China)Abstracter: Objective: To analyse the clinical characteristics of patients with overlap syndrome (OS) and evaluate the curative effect of OS patients with continue positive airway pressure (CPAP). Methods: Twenty patients with OS and 80 patients with obstructive sleep apnea syndrome (OSAS) were studied. Complications, weight index, respiratory disturbance index, and the lowest SaO2 during sleep were compared between the two groups, and the curative effect of OSAS after CPAP was evaluated. Results: The occurrence of hypertension, hyperlipemia and polycythemia, protein urine was higher in OS patients than OSAS group. There were obvious significances of weight index, respiratory disturbance index, and the lowest SaO2,course of disease during sleep were compared between two groups. After treatment, the lowest SaO2 during sleep of OS patient was increased; low ventilation index of OS was decreased; respiratory disturbance index was declined. Conclusion: There were more obvious clinical characteristics in OS patients. The occurrence of complications was highe and severe. Noninvasive ventilation was an effective treatment of OS patients. ......
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