失血性休克过程家兔皮层诱发电位的动态变化
皮层诱发电位,,失血性休克；,皮层诱发电位；,血压；,兔,1材料与方法,结果,3讨论,参考文献：
摘要: 目的：观察失血性休克过程中家兔大脑皮层电位变化的规律，了解失血性休克过程脑电位变化的病理生理基础。方法：按血压分组记录不同血压点诱发电位的幅度，血压每下降10 mmHg为一组，记录各时点皮层诱发电位的正波值、负波值及峰峰值，并进行组间比较。结果：皮层诱发电位随血压下降正波、负波 、峰峰值均有下降趋势，各血压组比较差异均有统计学意义(P<0.01)，正波值在90~70 mmHg (9.31~11.97 kPa) 时较平稳，70 mmHg(9.31 kPa)以下明显下降；负波值在90~80 mmHg (11.97~10.64 kPa)、70~60 mmHg (9.31~7.98 kPa)时变化不大，随后不断下降。结论：失血性休克过程中随血压下降诱发电位幅度的变化有一定规律，有利于临床治疗和监测。关键词：失血性休克； 皮层诱发电位； 血压； 兔
Experimental study on evoke cortical potential during hemorrhagic shock in rabbit
HUANG Qiang, KANG Fuxin, ZHANG Jianglong, et al
(Department of Physiology, Preclinical Medicine College, Xinjiang Medical University,Urumqi 830054, China)
Abstract: Objective: To investigate the rule of evoke cortical potential during hemorrhagic shock. To know about the basic principle of pathophysiology of the change of the brain's potential during hemorrhagic shock. Methods: According to blood pressure, evoke potential values of each blood pressure point were recorded and compared them. Seven rabbits were for this experiment. Results: With the blood pressure decreasing, positive wave values were decreasing (F=44.02, P<0.01), but it was static at 90~70 mmHg (11.97~9.31 kPa) , negative wave values were decreasing with the blood pressure decreasing(F=36.244, P<0.05), but at 90~80 mmHg (11.97~10.64 kPa)、70~60 mmHg (9.31~7.98 kPa) was static; pp values were tending to decreasing during this experiment(F=124.503, P<0.01). Conclusion: Evoke cortical potential has its regular change during hemorrhagic shock. It takes advantage to clinical treatment and supervise. ......
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