深冻_____异体骨;_自体骨髓;_移植;

深冻异体骨复合自体骨髓修复兔桡骨节段性骨缺损

http://www.100md.com 《新疆医科大学学报》 2005年第5期

深冻,,异体骨;,自体骨髓;,移植;,骨缺损,1材料与方法,2结果,3讨论,参考文献:

     摘要: 目的：研究兔深冻异体骨复合自体骨髓对节段性骨缺损的修复及其机制。方法：36只新西兰大白兔采用桡骨15 mm节段性骨缺损模型，随机分为3组，A组植入深冻异体骨复合自体骨髓，B组植入深冻异体骨，C组植入自体骨。术后不同阶段分别行大体、组织学及X线检测。结果：(1)3组骨缺损均有成骨现象发生;(2)A、C组骨生成、骨连接情况明显优于B组;(3)A、C组骨缺损愈合时间较B组明显缩短，A、C组骨缺损均于术后8周愈合，B组骨缺损在术后10周仍未愈合。结论：提示兔深冻异体骨复合自体骨髓具有良好的组织相容性及成骨作用，其取代自体骨植骨修复骨缺损具有可能性。

    关键词: 异体骨; 自体骨髓; 移植; 骨缺损

    Repairing radius segmental bone defects of rabbits with deeplowtemperature frozen allogeneic bone combined with autologous bone marrow

    ZHU Liang，Ahemat，WANG Zhenbin, et al

    (Department of Orthopaedics, First Affiliated Hospital, Xingjiang Medical University, Urumqi 830054, China)

    Abstract: Objective: To study repairing segmental bone defects with deeplowtemperaturefrozen allogeneic bone combined with autologous bone marrow of rabbits and its mechanism. Methods: The 15mm segmental bone defects were created on bilateral radius in 36 New Zealand rabbits and were divided into three groups. Group A received deeplowtemperaturefrozen allogeneic bone combined with autologous bone marrow, group B: deeplowtemperaturefrozen allogeneic bone, group C: autogenous bone. General observation, HE histologic section ......

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