【摘要】 目的 探讨按痤疮久治不愈的痤疮样皮损与圆形糠秕孢子菌(P.orb)感染的关系。 方法 对33例该类患者进行毛囊内容物镜检、真菌培养、病理检查及抗真菌治疗。 结果 22例(66.7%)患者阳性;P.orb阳性患者皮损数目与孢子数目存在相关性;16例P.orb阳性患者经抗真菌治疗，3例(18.7%)痊愈、6例(37.5%)显效。 结论 试验提示痤疮样皮损按痤疮久治不愈时，P.orb感染可能是重要原因之一。

    【关键词】 痤疮样皮损;圆形糠秕孢子菌

    A study on the relationship between the comedoid lesion resisted to the treatment and Pityrosporum orbiculare infection

    LIAO Jing-yun，GUO Han-xiang，GUO Sheng-tian.

    Department of Dermatologg，Longgang District Central Hospital of Shenzhen，Guangdong518116，China

    【Abstract】 Objective In order to understand the relationship between the comedoid lesion resisted to the treat-ment and pityrosporum orbiculare(P.orb)infection.Methods We investigated33cases of this kind of patients with-clinical microscopic cultural and therapeutic methods.Results 22(66.7%)were P.orb positive;The mumber of le-sion was correlated to the number of spores of P.orb;16cases of the P.orb positive patients were given itra-comaxole orally ......