【摘要】 目的 探讨采用超小剂量的甲基强的松龙佐治婴幼儿毛细支气管炎。方法 将112例毛细支气管炎患儿随机分为两组，对照组56例采用常规抗感染、抗病毒、镇静、喘乐宁氧泵吸入、氨茶碱2～3mg/(kg·次)，2～3次/d平喘及支持治疗。治疗组在常规治疗同时即加用甲基强的松龙1～2mg/(kg·d)，分1～2次静点。结果 治疗组呼吸急促、三凹征和肺部喘鸣音消失时间及住院天数等与对照组相比均明显缩短(P<0.01)。且甲基强的松龙使用天数、单次剂量、总剂量与已有报道相比，均明显减少。结论 在经过改进的常规疗法上，采用超小剂量甲基强的松龙佐治婴幼儿毛细支气管炎是可行的。

    【关键词】 甲基强的松龙；超小剂量；毛细支气管炎

    Clinical investigation of smaller doses methylprednisolonum on children with bronchiolitis

    SUN Li-ying.

    The Third Hospital of Xingtai City,Xingtai 054000,China

    【Abstract】 Objective To discuss the clinical effect of smaller doses methylprednisolonum on children with bronchiolitis.Methods 112 cases of bronchiolitis children were randomly divided into the observed group and the control group.While 56 control cases were treated with the regular anti-infection,anti-virus,and the support treatment,the 56 observed cases namely adds methylprednisolonum 1～2mg/(kg·d),which were dripped intravenously on bas's of routine therapy.Results Comparing with the control group,the disappearance times of short breath,lung sign and hospitalized days of the observed group obviously reduced(P<0.01).Also comparing with the past reports,the use number of days,the single inferior and the integral dose obviously reduced.Conclusion In the improvement routine treatment,uses smaller doses methylprednisolonum assistance treatment children with bronchiolitis is feasible. ......