左归丸促进骨髓形成肝细胞的研究
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李瀚旻, 高 翔, 晏雪生, 明安萍, 彭亚琴,
补肾;左归丸;骨髓移植;荧光原位杂交,李瀚旻,高翔,晏雪生,明安萍,彭亚琴,李晶津,通讯作者:,电话:,收稿日期:,接受日期:,PromotioneffectofZ
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李瀚旻, 高翔, 晏雪生, 明安萍, 彭亚琴, 湖北中医学院附属医院肝病研究所 湖北省武汉市 430061
李晶津, 武汉大学医学院2003级临床医学专业 湖北省武汉市 430071
李瀚旻, 男, 1956-05-17生, 湖北省利川市人, 土家族, 1992年湖北中医学院硕士研究生, 2000年湖北中医学院博士研究生毕业, 主任医师, 主要从事中西医结合治疗慢性肝病的基础与临床研究.
国家自然科学基金资助项目, No. 30271562, 30371787
湖北省自然科学基金资助项目, No. 2001ABB171
国家科技部重大基础研究前期研究专项, No. 2002CCC00300
通讯作者: 李瀚旻, 430061, 湖北省武汉市, 湖北中医学院附属医院肝病研究所. lihanmin69@126.com
电话: 027-88929180
收稿日期: 2005-09-21 接受日期: 2005-09-30
Promotion effect of Zuoguiwan on bone marrow cells’ forming into liver cells in mice
Han-Min Li, Xiang Gao, Xue-Sheng Yan, An-Ping Ming, Ya-Qin Peng, Jing-Jin Li
Han-Min Li, Xiang Gao, Xue-Sheng Yan, An-Ping Ming, Ya-Qin Peng, Institute of Liver Diseases, the Affiliated Hospital of Hubei Traditional Chinese Medicine College, Wuhan 430061, Hubei Province, China
Jing-Jin Li, 2003 Class of Clinical Medicine, School of Medicine, Wuhan University, Wuhan 430071, Hubei Province, China
Supported by Natural Science Foundation of China, No. 30271562, 30371787; Natural Science Foundation of Hubei Province, No. 2001ABB171; and the Early-stage Special Item of Basic Research of National Science and Technology Department of China, No. 2002CCC00300
Correspondence to: Dr. Han-Min Li, Institute of Liver Diseases, the Affiliated Hospital of Hubei Traditional Chinese Medicine College, Wuhan 430061, Hubei Province, China. lihanmin69@126.com
Received: 2005-09-21 Accepted: 2005-09-30
Abstract
AIM: To observe the influence of nourishing kidney (using Zuoguiwan) on the formation of liver cells from bone marrow cells.
METHODS: The female BALB/c mice were randomly divided into kidney nourishing group (KN, treated by Zuoguiwan), Qi-Xue restorative group (QXR, treated by Bazhentang) and control group (NC, treated by normal saline). After whole body irradiation with 9.0 Gy 60Co γ-rays, the female mice were injected via the tail vein with bone marrow cells from homogenic male mice to establish bone marrow transplantation model ......
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