角膜缘干细胞_____角膜缘干细胞；移植；翼状胬肉

角膜缘干细胞移植治疗翼状胬肉疗效的初步观察

http://www.100md.com 《滨州医学院学报》 2005年第6期

角膜缘干细胞,,角膜缘干细胞；移植；翼状胬肉,1资料与方法,2结果,3讨论,参考文献

     【摘要】目的观察胬肉切除联合角膜缘干细胞移植术治疗翼状胬肉的疗效，探讨降低翼状胬肉术后复发率的方法。方法选择翼状胬肉患者共24例28眼，按原发性胬肉和复发性胬肉分为两组，行胬肉切除联合自体角膜缘干细胞移植术。观察术后效果。结果角膜上皮修复时间为(31±03)d，原发性胬肉组与复发性胬肉组分别为(31±02) d和(33±05) d，P>005，总复发率为357%，原发性胬肉组0眼复发，复发性胬肉组1眼复发，P>005。22眼(786%)术后视力较术前有不同程度的提高，原发性胬肉组与复发性胬肉组视力提高分别为20眼和2眼，P<001。结论胬肉切除联合角膜缘干细胞移植术是一种治疗翼状胬肉较好的方法。

    【关键词】角膜缘干细胞；移植；翼状胬肉

    【中图分类号】 R77773

    Autologous corneal limbal stem cells transplantation for treatment of pterygium

    HU Jian JIA Hui ZHANG Jing

    Department of Ophthalmology,Binzhou Medical college,Binzhou 256603

    【Abstract】 Objective To investigate the therapeutic effects of autologous corneal limbal stem cells transplantation for treatment of pterygium,to approach the method to reduce postoperative recurrence rate.Methods Pterygium excision combined with autologous limbal stem cell transplantation was performed on 24 cases (28 eyes) with primary pterygium group or recurrent pterygium group.The result was analysed.Results The healing of corneal epithelial and autograft taked 31 days and 57 days respectively,all of which were stable.1 of 28 eyes(357%) was found recurence 2 months after operation.The visual acuity of most cases (786%) was promoted.Conclusion Autologous corneal limbal stem cells transplantation is an effective and safe treatment for primary and recurrent pterygium. ......

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