关键词: 骨质疏松症;骨折;弹性模量;极限强度

    摘 要:目的 探讨骨质疏松骨折愈合过程中骨痂局部生物力学性能的变化. 方法 利用SD大鼠骨质疏松胫骨骨折模型，测量了骨痂局部弹性模量和极限强度的变化. 结果 骨质疏松骨折愈合过程中，弹性模量和极限强度均随着骨折愈合过程的进行而增加，在骨折后35d编织骨完全形成后，极限强度与非骨折组相比无明显差别，而弹性模量有明显差别;而两者在同一时间点与正常骨折组相比均无明显差别. 结论 骨质疏松骨折骨痂局部的弹性模量及极限强度的变化模式与正常骨折骨痂相比无明显差别.

    Biomechanical changes of local bone callus in osteo┐porotic bone healing

    ZHANG Sheng-Li，WANG Quan-Ping

    Institute of Orthopaedics of Chinese PLA，Xijing Hospital，Fourth Military Medical University，Xi'an710033，China

    Keywords:osteoporosis;fracture;elastic modulus;maxi-mum intensity

    Abstract:AIM To research the changes of the biomechanics of the local bone callus in the process of osteoporotic bone healing.METHODS The elastic modulus and maximum in-tensity in the local callus were measured using osteoporotic tibial fracture model.RESULTS The values of elastic mod-ulus and maximum intensity increased with the proceeding of the osteoporotic bone healing.There were significant differ-ence in the maximum intensity but not in the elastic modulus at fracture day35compared with the non-fracture group.But there was no significant difference at the identical time points between two groups.CONCLUSION There may be no sig-nificant difference in the changing model of the elastic modu-lus and the maximum intensity between the osteoporotic and normal groups. ......