关键词: 霍奇金病;淋巴细胞;增生

    摘 要:目的 认识霍奇金病(Hodgkin's Disease，HD)组织中的淋巴细胞的增生性质. 方法 应用PCNA免疫组化方法测定经石蜡包埋40g·L-1 甲醛固定的10例HD和10例反应性增生淋巴结标本的增生活性. 结果 10例HD病的背景淋巴细胞平均增生分数为(17.92±7.1)%，10例反应性增生淋巴结淋巴细胞平均增生分数为(11.14±8.6)%，统计学分析表明两者的增生分数有非常显著的差异(χ2 =75.6，P<0.001). 结论 霍奇金病中淋巴细胞较反应性增生淋巴结淋巴细胞的增生分数显著升高，表明它们可能不是反应性淋巴细胞.

    Analysis of the proliferative activity of background lymphoid cells in Hodgkin's disease

    GUO Ying，HUANG Gao-Sheng，YAN Qing-Guo，WANG Zhe，ZHANG Yong-Qing

    Department of Pathology，Faculty of Preclinical Medicine，Fourth Military Medical University，Xi'an710033，China

    Keywords:Hodgkin's disease;lymphoid cell;hyperplasia

    Abstract:AIM To find out the nature of lymphoid cells in the tissue of Hodgkin's disease，based on estimating prolifer-ative activity.METHODS By using an antibody to prolifer-ating cell nuclear antigen(PCNA) ......