关键词: 假关节;胫骨;病理学

    摘 要:目的 探讨先天性胫骨假关节(CPT)的发病部位及病理特点. 方法 对28例CPT不同部位的70个标本进行了大体显微镜及电镜观察. 结果 CPT骨膜及断端间有大量的致密纤维结缔组织增生，压迫和侵蚀胫骨.病变组织由大量高分化纤维母细胞、少量肌纤维母细胞和大量胶原纤维构成.未见异常神经成分. 结论 CPT是一种起源于骨膜的纤维瘤病所造成的病理性骨折、骨不连，它的发病与神经纤维瘤病无直接关系.

    Histopathological study of congenital pseudarthrosis of the tibia

    LEI Wei，CUI Geng，HUANG Yao Tian，LU Rong，YANG Guang

    Institute of Orthopedics of Chinese PLA，Xijing Hospital，Fourth Military Medical University，Xi'an710033，China

    Keywords:pseudarthrosis;tibia;pathology

    Abstract:AIM To investigate the pathological changes and origin of congenital pseudarthrosis of tibia(CPT).METH┐ODS Seventy different specimens were taken from28CPT patients.By macroscopy，microscopy，electronic microscopy all specimens were studied after fixation and dyeing.RE┐SULTS The soft tissue interposed dense connective tissues were proliferated between the CPT bone ends and periosteum which compressed and eroded the tibia.There were a large number of cellular components and collagen fibers in the pro-liferated dense connective tissues ......