关键词: 子宫内肿瘤;T细胞;红细胞;Ag-NORs

    摘 要:目的 探讨子宫内膜癌患者的免疫功能变化及临床意义. 方法 采用单克隆抗体直接免疫荧光染色法、红细胞花环试验及KL型肿瘤免疫图象分析仪，对21例子宫内膜癌患者和20名正常对照组分别测定其外周血T细胞亚群、红细胞免疫C3 b受体花环率(E-C3 bRR%)与红细胞循环免疫复合物花环率(ICR%)、核仁银染区面积/细胞核面积比值(I.S%). 结果 子宫内膜癌患者CD+3 T细胞，CD+4 T细胞，CD+4 /CD+8 比值，E-C3 bRR%，I.S%值明显降低;CD+8 T细胞，E-ICR%明显升高，与对照组相比较差异显著(P<0.01). 结论 子宫内膜癌患者免疫功能低下;联合检测T细胞亚群、红细胞免疫与Ag-NORs可较全面反映子宫内膜癌患者的免疫功能状态，并可指导临床治疗.

    Significance of T lymphocyte subset，erythrocyte immune function and Ag┐NORs in nucleolar orga┐nizer regions in patients with carcinoma of en┐dometrium

    XU Li-Yan ZhANG Ying-Hua YIN Guo-Wu ZHANG Li-Chao YIN Ying HAO Xiao-Ke

    1 Central Laboratory，

    2 Department of Obstetrics and Gynecology，Tangdu Hospital，Fourth Military Medical University，Xi'an710038，China

    Keywords:endometrial neoplasms;T lymphocyte;erythro-cyte;Ag-NORs

    Abstract:AIM To study the significance of T lymphocyte subset erythrocyte immune function and argyrophilic protein in nucleolar organizer regions(Ag-NORs)in patients withcarcinoma of the endometrium.METHODS CD+3 T cell ......