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纤溶酶治疗恢复期脑梗死疗效观察
http://www.100md.com 《中华现代内科学杂志》 2006年第1期
恢复期脑梗死,,恢复期脑梗死;纤溶酶;疗效,1资料与方法,2结果,3讨论,【参考文献】
     【摘要】 目的 探讨纤溶酶治疗恢复期脑梗死的疗效。方法 设对照组32例应用尼莫地平40mg,每日3次,脑复康0.8g,每日3次。治疗组32例,在对照组治疗基础上静脉滴注纤溶酶100u,每日1次。每14天为1个疗程。结果 治疗组治愈9例,显著进步13例,进步7例,总有效率90.6%;对照组痊愈5例,显著进步8例,进步11例,总有效率75.0%。两组疗效比较,治疗组疗效显著优于对照组(P<0.05)。治疗组治疗后血液流变学较治疗前和对照组治疗后有明显改善(P<0.05或P<0.01)。结论 纤溶酶治疗恢复期脑梗死疗效确切,安全可靠。

    【关键词】 恢复期脑梗死;纤溶酶;疗效

    Curative efficacy of fibrinolysin in treatment of cerebral infarction

    SHA Ya-bin,GAO Cheng-zhi,QIAO Feng.

    The First People’s Hospital of Jinan,Jinan 250022,China

    【Abstract】 Objective This research is on the curative effect of fibrinolysin on the cerebral infarction in convalescence.Methods 32 cases in control group were administered 40 mg nimodipine three times a day, and 0.8g naofukang three time a day. 32 cases in experimental group, besides the nimodipine and naofukang as the cases in control group, were instilled intravenously 100u fibrinolysin once a day. 14 days is a course of treatment in both groups. Results 9 cases were cured, 13 were improved remarkably and 7 were improved in experimental group. The general effective rate is 93.6%. 5 cases were cured, 8 were improved remarkably and 11 were improved in control group. The general effective rate is 70%. After comparison, the curative effect in experimental group has a marked advantage of that of the control group (P<0.05). There is great improvement in cases of the experimental group in rheological property of the blood after treatment (P<0.05 or P<0.01). Conclusion The curative effect of fibrinolysin on the cerebral infarction in convalescence is definite and it is safe to administer fibrinolysin. ......

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