关键词: 冠状动脉疾病;糖尿病;侧支循环;心排出量;心室功能，左

    摘 要:目的 评价糖尿病(DM)对冠状动脉侧支血管(CCVs)及左室功能的影响. 方法 选择1995-08-01/2000-10-30做过冠脉造影的DM患者(排除冠脉造影正常和狭窄程度<75%的病例)212例为DM组;另选择同期入院的212例非糖尿病(NDM)并至少有一支冠脉狭窄≥75%的患者作为对照组.根据Rentrop分级方法对患者的侧支循环进行评分.行左室造影测量左室射血分数(LVEF). 结果 两组冠脉狭窄程度相似，但病变血管数目DM组(1.78±0.60)个明显高于NDM组(1.43±0.62)，P<0.01.平均侧支评分DM组为(2.32±2.11)，DM组为(2.68±2.26)，P<0.01.左室射血分数(LVEF)DM组为(48±27)%，明显低于NDM组(61±22)%，P<0.01. 结论 DM组较NDM组侧支循环形成不良，左室射血分数偏低，说明DM是冠脉侧循环形成的抑制因素，并且影响左室功能.

    Effect of diabetes mellitus on formation of coronary collateral vessels and left ventricular ejection func┐tion in patients with coronary artery disease

    DAI Zheng-Xue，JIA Guo-Liang，WANG Hai-Chang，ZHANG Yu-Shun，LI Wei-Jie，LI Cheng-Xiang，LIU Bin

    Department of Cardiology，Xijing Hospital，Fourth Military Medical University，Xi'an710033，China

    Keywords:coronary disease;diabetes mellitus;collateral cir-culation;cardiac output;ventricular function，left

    Abstract:AIM To evaluate the effect of diabetes mellitus(DM)on coronary collateral vessels(CCVs)and left ventric-ular ejection function in patients with coronany heart disease. ......