Preliminary evaluation of cerebral gliomas by MR perfusion weighted imaging

    DU Weiª²Qing, DENG Jingª²Lan, HUAN Yi, WANG Jing, GE Yaª²Li, YANG Chunª²Min, YANG Yan, CHANG Yingª²Juan

    1Department of Radiodiagnosis, 2Department of Nuclear Medicine, Xijing Hospital, Fourth Military Medical University, Xi¬ðan 710033, China

    ¡¾Abstract¡¿ AIM: To evaluate the diagnostic value of magnetic resonance (MR) perfusion weighted imaging (PWI) in cerebral gliomas. METHODS: Conventional MRI and PWI were performed in 26 patients with histologically confirmed gliomas. The perfusion data were processed to obtain a color map of cerebral blood volume (CBV) and the maximal relative CBV (rCBV) of each lesion was computed with a nondiffusible tracer model. RESULTS: The maximal rCBV in lowª²grade gliomas varied from 0.72 to 4.26, with a mean of (2.10¡À1.18), and in the highª²grade cohort varied from 0.89 to 10.02, with a mean of (5.23¡À1.86). This difference in maximal rCBV between two groups was statistically significant (P<0.01; Student t test). CONCLUSION: MR perfusion weighted imaging is useful in the preoperative assessment of tumor grade and in providing vascular information, which can not be obtained by conventional MR imaging. ......