Significance of administration of a quick action hypnotic in PSG examinations in insomnia

    GUO Xiaoª²Ming, SU Changª²Jun, YOU Guoª²Xiong, ZHANG Yanª²Guo, YANG Ting

    Sleep Center of Combined Western and Traditional Chinese Medicine, Tangdu Hospital, Fourth Military Medical University, Xi¡¯an 710038, China

    ¡¾Abstract¡¿ AIM: To reduce the interference of frequent awakenings (FA) in polysomnogram (PSG). METHODS: PSG was first performed in 30 insomniacs and a second 2nd PSG was done in another room after they took Midazolum (Mm) 7.5 mg before sleep. The results of the second PSG were compared with those of the first one(at intervals of 10 d)and with clinic findings. RESULTS: Midazolum significantly shortened the sleep latency (44¡À73) min vs (13¡À12) min, P<0.01, REM latency (180¡À82) min vs (124¡À55) min, P<0.01 and decreased the frequency of first sleep cycle awaking (4.6¡À3.4) vs (2.0¡À2.7), P<0.01. After taking midazolum, the insomniacs with first night effect (FNE) reduced from 23 to 5 cases and the insomniacs who showed REM sleep latency (RSL) without awaking increased from 2 to 11 cases, among whom 4 cases were RSL<90 min, 2 cases RSL>120 min and 5 cases RSL 90-120 min. They all well matched the clinical diagnosis of depression or dysthemia, encephalopathy and psychoª²physiologix insomnia, respectively. The cases of REM latency consistent with clinic diagnosis increased from 12 to 26 patients (P<0.01). CONCLUSION: For PSG examination, the application of midazolum before sleep can effectively reduce the frequent awakenings, thus improving the accuracy of PSG. ......