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肾缺血再灌注损伤中CD11a及髓过氧化酶的变化
http://www.100md.com 《第四军医大学学报》 2003年第8期
淋巴细胞,,淋巴细胞,功能相关,抗原1;CD11a;髓,过氧化酶;肾,缺血再灌注,损伤,0引言,1材料和方法,2结果,3讨论,【参考文献】
     (第四军医大学西京医院泌尿外科, 陕西 西安 710033,解放军309医院泌尿外科, 北京 100091)

    【关键词】 淋巴细胞,功能相关,抗原1;CD11a;髓,过氧化酶;肾,缺血再灌注,损伤

    【Abstract】 AIM: To investigate the change of CD11a and myeloperoxidase (MPO) content during rat renal ischemia-reperfusion injury (IRI), as well as the role of LFA1 in renal IRI. METHODS:We utilized the rat model of renal IRI to detect the renal tissue contents of CD11a and MPO. RESULTS: Level of CD11a and MPO was very low in normal renal tissue, but was increased significantly in those of ischemia reperfusion. And this level in the ischemia 60 min reperfusion group was higher than that in ischemia 30 min reperfusion group. CONCLUSION: Level of CD11a and MPO in rat renal tissue increased significantly during rat renal IRI. LFAK1 mediated leukocyte adherence plays an important role in renal IRI.

     0 引言

    肾脏缺血再灌注损伤(ischemia reperfusion injury ......

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