肝癌组织RhoC蛋白表达与微血管密度的关系
http://www.100md.com
邱兴烽, 王效民, 殷 平, 陈守惠, 纪毅馨
肝癌;转移;RhoC蛋白;微血管密度,邱兴烽,王效民,殷平,陈守惠,纪毅馨,邱兴烽,通讯作者:,ExpressionofRhoCproteinandi
 |
| 第1页 |
参见附件(904KB，5页)。
邱兴烽, 王效民, 福建医科大学, 厦门大学附属中山医院肝胆外科 福建省厦门市 361004
殷平, 陈守惠, 纪毅馨, 厦门大学附属中山医院病理科 福建省厦门市 361004
邱兴烽, 福建医科大学2003级硕士, 助教, 主要从事肝癌侵袭转移的研究.
通讯作者: 王效民, 361004, 福建省厦门市湖滨南路201号, 厦门大学附属中山医院肝胆外科. wxm@xmzsh.com
电话: 0592-2292203
收稿日期: 2005-12-23 接受日期: 2006-02-11
Expression of RhoC protein and its relationship with microvessel density in hepatocellular carcinoma
Xing-Feng Qiu, Xiao-Min Wang, Ping Yin, Shou-Hui Chen, Yi-Xin Ji
Xing-Feng Qiu, Xiao-Min Wang, Department of Hepatobiliary Surgery, Zhongshan Hospital, Fujian Medical University, Xiamen 361004, Fujian, China
Ping Yin, Shou-Hui Chen, Yi-Xin Ji, Department of Pathology, Zhongshan Hospital, Fujian Medical University, Xiamen 361004, Fujian Province, China
Correspondence to: Dr. Xiao-Min Wang, Department of Hepatobiliary Surgery, Zhongshan Hospital, 201 Hubin South Road, Xiamen 361004, Fujian Province,China. wxm@xmzsh.com
Received: 2005-12-23 Accepted: 2006-02-11
Abstract
AIM: To explore the expression of RhoC protein and its relations with microvessel density (MVD) in hepatocellular carcinoma (HCC).
METHODS: Immunohistochemical staining was used to detect the expression of RhoC protein and MVD in the tissues from HCC (n = 49), metastatic focus of HCC and normal liver (n = 9). The relationship between the RhoC expression and pathological features as well as MVD was evaluated.
RESULTS: The positive rate of RhoC expression was 73.5% (36/49) in HCC, 81.8% (18/22) in the metastatic focus of HCC and 11.1% (1/9) in normal liver tissues, and there was significant difference between the former two and the latter (P < 0.01). The expression of RhoC protein in HCC was not correlated with the age, gender of patients, tumor size, α-fetoprotein expression, HBsAg and tumor encapsulation (P > 0.05), but significantly correlated with the Edmondson grading (χ2 = 8.037, P = 0 ......
您现在查看是摘要介绍页，详见PDF附件(904KB，5页)。