关键词: 肝豆状核变性;辅助性原位活体肝部分移植

    摘 要:目的 探讨辅助性原位活体肝部分移植治疗肝豆状核变性(HLD)的可行性. 方法 受体女性，20岁，O型血，因肝豆状核变性而接受辅助性原位活体肝部分移植.供体男性，21岁，A型血.手术切除受体原病肝左外叶260g，取供体左外叶肝脏295g原位移植于受体.术前行血浆交换，术后以FK506、激素、环磷酰胺联合免疫抑制，手术前后辅以排铜药物治疗. 结果 患者已生存半年余，基本恢复正常生活，移植肝脏体积明显增大，肝功能正常，临床症状及生化指标均缓解. 结论 辅助性原位活体肝部分移植是治疗肝豆状核变性的有效方法.

    Partial orthotopic living liver transplantation for Wilson's disease

    WANG Hong-Guang，GUAN Wen-Xian，DOU Ke-Feng，LI Kai-Zong

    Department of Hepatobiliary Surgery，Xijing Hospi-tal，Fourth Military Medical University，Xi'an710033，China

    Keywords:Wilison's disease;partial orthotopic liver trans-plantation

    Abstract:AIM To investigate the feasibility of auxiliary partial orthotopic liver transplantation(APOLT)from a liv-ing donor to treat Wilson's disease.METHODS The patient was a20-year-old girl with Wilson's disease，whose blood type was O.The donor was a man aged21and his blood type was A.The graft(295g)，left lateral lobe of donor's liver，was implanted after resection of the left lateral segment(260g)of the native liver.Considering there was a different blood type between donor and recipient ......