MSCT vascular reconstruction and double chemoembolization through portal vein and liver artery in 25 patients with liver cancer metastases

    CHEN Xiong, PENG Yongª²Hai, OUYANG Xueª²Nong, LI Tianª²Ran

    Department of Oncology, Fuzhou General Hospital, Nanjing Military Area Command, Fuzhou 350025, China

    ¡¾Abstract¡¿ AIM: To study the effect of MSCT vascular reconstruction and chemoembolization through portal vein and liver artery in patients with liver cancer metastases. METHODS: Twentyª²five patients (male 18, female 7) with liver cancer metastases were randomized into 2 groups. In all these patients, the hepatic vessels were restructured with MSCT while 11 patients in control group received only transcatheter arterial chemoembolization (TACE) therapy and 14 patients received TACE 1 week after portal vein chemoembolization in the treatment group. TACE was steered by digital Xª²ray and percutaneous iodized oil portal vein injection was steered by colorª²ultrasonic imaging. The white blood cell level, hepatic function, tumor size and life quality were observed before and after treatment. RESULTS: All the hepatic arteries and portal veins were successfully restructured and ¢ôª²¢õgrade hepatic blood vessels were seen clearly in images from DSA and colorª²ultrasonic imaging. We found that in 60% cases, hepatic artery was the main vessel supplying blood to tumors while in 40% cases, tumors were surrounded by portal veins and the blood were supplied by portal veins. In large tumors, the center part was necrotic and had no blood supply. No significant differences were found in the size of tumors or in the levels of WBC, TBIL, ALT and life quality between control and treatment groups(P>0.05). CONCLUSION: Vascular restructure with MSCT and chemoembolization through portal vein and liver artery, with no obvious sideª²effects, are effective for patients with liver cancer metastases. ......