关键词: 癌，肝细胞;导管插入术，外周;输注，动脉内;化学栓塞;治疗性;预后

    摘 要:目的 探讨中晚期肝癌介入化疗后的主要预后影响因素. 方法 对81例行介入化疗的中晚期肝癌病例进行回顾性统计，应用COX比例风险模型对14项指标进行了多因素分析，并用Kaplan-Meier法计算其生存率. 结果 多变量分析显示，影响中晚期肝癌预后最明显的因素是肿瘤大体类型、门静脉癌栓、经手术治疗;经肝动脉插管灌注化疗组与经肝动脉插管化疗栓塞组的预后无差异.本组6，12，24，30mo生存率分别为58%，32%，15%，12%. 结论 中晚期肝癌预后由多种因素决定.对于肿瘤相对局限、无门静脉癌栓的患者积极行介入化疗术，可获得较好的疗效.

    Prognostic factors in patients with advanced hepato┐cellular cancer after transcatheter arterial chemo┐embolization

    NAN Ke-Jun SUI Cheng-Guang WEI Yong-Chang LI Chun-Li LI Yi YANG Jin CHEN Ling LIU Ya-Min

    1 Department of Oncology，

    2 Medical Imaging Cen-ter，First Hospital，Xi'an Jiaotong University，Xi'an710061，China

    Keywords:carcinoma，hepatocellular;catheterization，pe-ripheral;infusions，intra-arterial;chemoem-bolization，therapeutic;prognosis

    Abstract:AIM To evaluate the major prognostic factors in advanced hepatocellular carcinoma(HCC)after transcatheter arterial chemoembolization(TACE)and transcatheter arteri-al infusion chemotherapy(TAI).METHODS Retrospective analysis of14factors for prognosis were studied by multivari-able analysis with COX proportional hazards survival model in cases of HCC treated by interventional chemotherapy via hepatic artery ......