【摘 要】 目的 介绍细菌内毒素法对甘油氯化钠注射液热原的研究。 方法 应用鲎试剂检查甘油氯化钠注射液的热原，观察甘油氯化钠注射液对细菌内毒素检查法的干扰现象。 结果 甘油氯化钠注射液稀释2倍对细菌内毒素检查法无干扰行为。 结论 对甘油氯化钠注射液进行2倍稀释以0.5EU/ml的鲎试剂检查其热原是可行的。 【关键词】 甘油氯化钠注射液;细菌内毒素;鲎试剂

    Study of bacterial endotoxin test for compound glycerin injection ZHANG Hao，ZHANG Da-ping，LIN Yu-hong，et al.(De-partment of Pharmacy，Affiliated Hospital of Bengbu Medical College，Anhui233004，China)

    【Abstract】 Objective To introduce a method to study the bacterial endotoxin test for detecting pyrogen in compound glycerin injection.Methods Limulus reagent was applied to detect pyrogen in compound glycerin injection and interference of compound glycerin injection in the process of bacterial endotoxin test was observed.Results Compound glycerin injection in2-fold dilution had no interference in the bacterial endotoxin test.Conclusion Compound glycerin injection in2-fold dilution applied in0.5EU/ml limulus reagent in detection of its pyrogen is feasible.

    【Key words】 Compound glycerin injection;Bacterial endotoxin;Limulus reagent

    静脉给药过程中有时会发生热原反应 ......