摘 要：目的：研究蝎毒对家兔凝血功能的影响,以探讨蝎毒抑制凝血功能的机制。方法：10只家兔分别于给药前1h、给药后1h、给药后2h抽血1.8ml，检测凝血酶原时间、部分凝血酶原时间、纤维蛋白原含量。将给药后1h、给药后2h凝血酶原时间、部分凝血酶原时间、纤维蛋白原含量分别与给药前1h比较。结果：本实验中测定的凝血酶原时间、部分凝血酶原时间，在给药1h明显延长，与给药前相比具有差异显著性。在给药2h凝血酶原时间、部分凝血酶原时间比1h缩短，与给药前相比无差异显著性。结论:蝎毒对家兔凝血功能的影响除通过降低血液粘度外，还可能是蝎毒影响了凝血因子的功能所致。

    关键词： 蝎毒; 凝血功能

    Influence of Scorpion Venom on the blood Coagulation Function of Rabbits

    ZOU Ming-zhi

    (Lianjiang People's Hospital, Guangdong Lianjiang 524400,China)

    Abstract：Objective： Research the influence of Scorpion Venom on the blood coagulation function of rabbits and discuss the mechanism of Scorpion Venom restraining the blood coagulation function.Methods： All of 10 rabbits were abstracted 1.8ml blood 1 hour before rabbits recepting Scorpion Venom,1 hour and 2 hours after rabbits recepting Scorpion Venom.PT,APTT,FIB in blood of rabbits were examined. We compared the results of PT,APTT,FIB of 1 hour and 2 hours after rabbits recepting Scorpion Venom with the results of 1 hour before rabbits recepting Scorpion Venom.Results： The results of PT,APTT,FIB of 1 hour after rabbits recepting Scorpion Venom prolonged evidently.There was difference between the results of 1 hour after rabbits recepting Scorpion Venom and the results of 1 hour before rabbits recepting Scorpion Venom. There was no difference between the results of 2 hours after rabbits recepting Scorpion Venom and the results of 1 hour before rabbits recepting Scorpion Venom.Conclusion： The mechanism of Scorpion Venom restraining the blood coagulation probably function are that Scorpion Venom reduce blood viscosity and affects the function of blood coagulation factors. ......