愈风宁心_____愈风宁心微丸；_愈风宁心片；葛根素

愈风宁心微丸与愈风宁心片溶出度的比较研究

http://www.100md.com 《时珍国医国药》 2006年第1期

愈风宁心,,愈风宁心微丸；,愈风宁心片；葛根素,1仪器与试药,2方法与结果,3讨论,参考文献：

     摘要：目的探讨愈风宁心微丸与其片剂的溶出速度。方法采用转篮法测定两者的体外溶出度，以葛根素不同时间溶出度为测定指标。结果愈风宁心微丸的Td为4.8 min,T50为4.3 min; 而愈风宁心片的Td为61 min，T50为45 min。结论二者葛根素溶出具有明显的差异，微丸的溶出速度快于片剂。

    关键词：愈风宁心微丸；愈风宁心片；葛根素

    Comparison of the Dissolution Rate of Yufengningxi Micro-pills and Yufengningxin Tablets

    CHENG Lan, YUAN Zimin, ZHAO Lin, LI Ruihai, L Jia, CHEN Cuiying

    (College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China)

    Abstract:ObjectiveTo study the difference of dissolution between Yufengningxin Micro-pills and Yufengningxin Tablets.MethodsBasket-stirring method was used to determine the dissolution rate by determining the dissolubility of puerarin at different time.ResultsYufengningxin Micro-pills:Td is 4.8min and T50 is 4.3 min; Yufengningxin Tablets:Td is 61 min and T50 is 45 min.ConclusionThere is significant difference of the dissolution between the two kinds of preparations. Dissolution of Yufengningxin Micro-pills is better than Yufengningxin Tablets.

    Key words:Yufengningxin Micro-pills; Yufengningxin Tablets;Puerarin

    微丸作为丸剂剂型中的一种 ......

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