摘要 :目的 探讨胃肠内补液救治高渗性非酮症糖尿病昏迷(HNDC)的临床疗效。 方法 32例HNDC患者，18例采用胃肠内补液联合静脉补液方法治疗(胃肠内补液组)，14例采用常规静脉补液方法治疗(常规治疗组)，观察2组患者治疗前和治疗后6、24、48h血生化指标及血浆渗透压的变化，观察病情变化、并发症和病死率。 结果 胃肠内补液治疗后6、24、48h血糖、血钠、血钾、血尿素氮、血浆渗透压较快恢复正常，患者清醒早、补液量少，有效降低了心力衰竭、脑水肿的发生和病死率。 结论 胃肠内补液救治HNDC疗效优于传统的静脉补液治疗，且简单易行、安全高效。

    关键词 :胃肠内补液;糖尿病;高渗性非酮症昏迷;血浆渗透压

    Clinical value of gastroenteric fluid replacement for hyperosmolar nonketotic diabetic coma

    LI Wei，ZHANG Hong，YIN Song-lou，et al

    (Department of Endocrinology，Affiliated Hospital of Xuzhou Medical College，Xuzhou，Jiangsu221002，China)

    Abstract:Objective To investigate the clinical value of gastroenteric fluid replacement for hyperosmolar nonketotic dia-betic coma(HNDC).Methods Thirty-two patients with HNDC were randomly divided into two groups to undergo combined gastroenteric and venous fluid replacement(gastroenteric fluid group，n=18)and common venous fluid replacement(common treatment group ......